Endocrine Abstracts

The 1-mg overnight dexamethasone suppression test (DST) is a screening test for endogenous Cushing’s syndrome (CS). The principle is that dexamethasone (D) will suppress ACTH and cortisol (C) secretion in healthy individuals, but not in CS. We have studied the associations between D and C concentrations in patients without CS after 1-mg DST.Methods: On suspicion of CS, 59 patients received 1-mg D at 23 p.m. and next day at 8 a.m. blood was drawn for...